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single cell portal database  (Broad Clinical Labs)


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    Structured Review

    Broad Clinical Labs single cell portal database
    Single Cell Portal Database, supplied by Broad Clinical Labs, used in various techniques. Bioz Stars score: 96/100, based on 899 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/single+cell+portal+database/Single+Cell+Sequencing/pmc13157535-174-1-6
    Average 96 stars, based on 899 article reviews
    single cell portal database - by Bioz Stars, 2026-10
    96/100 stars

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    Related Articles

    Single Cell:

    Article Title: Identification of Cell Subpopulation-Specific Driver Genes Reveals Ideal Candidates for Renal Cell Carcinoma Immunotherapy
    Article Snippet: .. Single-cell RNA sequencing data for RCC was obtained from the Single Cell Portal database (https://singlecell.broadinstitute.org/single_cell, accessed on 14 December 2024). ..

    Article Title: Network model for alignment, stitching and slice-to-volume 3D reconstruction of large-scale spatially resolved slices.
    Article Snippet: .. The634 mouse brain (8 months) data [42] and mouse hippocampus data [43] used in this study635 are available in the Single Cell Portal database under accession codes SCP1375 (https:636 //singlecell.broadinstitute.org/single cell/study/SCP1375) and SCP1830 (https://637 singlecell.broadinstitute.org/single cell/study/SCP1830). ..

    Article Title: Identification and Validation of Key Purine Metabolism-Related Genes in Ulcerative Colitis Using Bioinformatics and Machine Learning
    Article Snippet: .. We visualized the distribution of key UCDE-PMRGs in UC colonic immune cells and epithelial cells through the Single cell portal database ( https://singlecell.broadinstitute.org/single_cell ). ..

    Article Title: Identification of Cell Subpopulation-Specific Driver Genes Reveals Ideal Candidates for Renal Cell Carcinoma Immunotherapy
    Article Snippet: .. Single-cell RNA sequencing data for RCC were retrieved from the Single Cell Portal database (https://singlecell.broadinstitute.org/single_cell, accessed on 14 December 2024), encompassing five patients who received immunotherapy (patient identification: P55, P915, P913, P906 and P912) and three patients who did not receive systemic treatment (patient identification: P76, P90 and P916). ..

    Article Title: Expressional and prognostic value of cytokine receptor-like factor 3 in liver hepatocellular carcinoma patients via integrated bioinformatics analyses and experiments
    Article Snippet: .. The Single Cell Portal database ( https://singlecell.broadinstitute.org/single_cell ) is an online resource for the analysis and exploration of single-cell sequencing data. ..

    Article Title: Network model for alignment, stitching and slice-to-volume 3D reconstruction of large-scale spatially resolved slices.
    Article Snippet: .. The spatial multi-omics mouse brain data [56] used in this study648 are available in the Single Cell Portal database under accession code SCP1835 (https:649 //singlecell.broadinstitute.org/single cell/study/SCP1835). ..

    Article Title: High expression of GOLM1 predicts poor prognosis and unfavorable immunotherapy efficacy in breast cancer patients
    Article Snippet: .. The Single Cell PORTAL database (https://singlecell. broadinstitute.org/single_cell) was used for the visualization of GOLM1 expression in GSE176078. ..

    Article Title: The E3 ubiquitin ligase TRIM4 promotes the proliferation of glioblastoma by inhibiting ABTB1-mediated CDK1 ubiquitination.
    Article Snippet: Background: Emerging evidence has implicated the multifaceted roles of TRIM proteins in glioblastoma; however, the function of TRIM4 in glioblastoma pathobiology has not been clarified.. Methods: The clinical significance of TRIM4 was elucidated through analysis of the TCGA and CGGA databases.. Its function was achieved via cellular functional assays and the Xenograft tumor model employing lentivirus in LN-229 and T98G cells.

    RNA Sequencing:

    Article Title: Identification of Cell Subpopulation-Specific Driver Genes Reveals Ideal Candidates for Renal Cell Carcinoma Immunotherapy
    Article Snippet: .. Single-cell RNA sequencing data for RCC was obtained from the Single Cell Portal database (https://singlecell.broadinstitute.org/single_cell, accessed on 14 December 2024). ..

    Article Title: Identification of Cell Subpopulation-Specific Driver Genes Reveals Ideal Candidates for Renal Cell Carcinoma Immunotherapy
    Article Snippet: .. Single-cell RNA sequencing data for RCC were retrieved from the Single Cell Portal database (https://singlecell.broadinstitute.org/single_cell, accessed on 14 December 2024), encompassing five patients who received immunotherapy (patient identification: P55, P915, P913, P906 and P912) and three patients who did not receive systemic treatment (patient identification: P76, P90 and P916). ..

    Sequencing:

    Article Title: Expressional and prognostic value of cytokine receptor-like factor 3 in liver hepatocellular carcinoma patients via integrated bioinformatics analyses and experiments
    Article Snippet: .. The Single Cell Portal database ( https://singlecell.broadinstitute.org/single_cell ) is an online resource for the analysis and exploration of single-cell sequencing data. ..

    Biomarker Discovery:

    Article Title: Network model for alignment, stitching and slice-to-volume 3D reconstruction of large-scale spatially resolved slices.
    Article Snippet: .. The spatial multi-omics mouse brain data [56] used in this study648 are available in the Single Cell Portal database under accession code SCP1835 (https:649 //singlecell.broadinstitute.org/single cell/study/SCP1835). ..

    Expressing:

    Article Title: High expression of GOLM1 predicts poor prognosis and unfavorable immunotherapy efficacy in breast cancer patients
    Article Snippet: .. The Single Cell PORTAL database (https://singlecell. broadinstitute.org/single_cell) was used for the visualization of GOLM1 expression in GSE176078. ..

    Article Title: The E3 ubiquitin ligase TRIM4 promotes the proliferation of glioblastoma by inhibiting ABTB1-mediated CDK1 ubiquitination.
    Article Snippet: Background: Emerging evidence has implicated the multifaceted roles of TRIM proteins in glioblastoma; however, the function of TRIM4 in glioblastoma pathobiology has not been clarified.. Methods: The clinical significance of TRIM4 was elucidated through analysis of the TCGA and CGGA databases.. Its function was achieved via cellular functional assays and the Xenograft tumor model employing lentivirus in LN-229 and T98G cells.



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    Broad Clinical Labs single cell portal database
    Single Cell Portal Database, supplied by Broad Clinical Labs, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/single+cell+portal+database/Single+Cell+Sequencing/pmc13157535-174-1-6
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    Broad Institute Inc single cell portal database
    Expression of CSF ligands in murine glioma and human GBM: ( A ) Murine KR158B gliomas express the CSF ligands M-CSF and IL-34 but not GM-CSF. KR158B cells were plated at different numbers (50, 100, 200 thousand) in 24 well plates and the conditioned media were subjected to ELISA after 24 h for cytokine quantification. CSF1R ligands, M-CSF and IL-34, were found at a higher concentration in the media compared to GM-CSF (n = 3 experiments). ( B ) Human GBM expression of CSF ligands was determined from a search of the OncoDB <t>database.</t> TCGA dataset was queried for GBM gene expression. Results were compared to normal brain tissue from GTEx. CSF-1 (M-CSF) was differentially upregulated in the GBM microenvironment (n = 148 patients) compared to normal brain (n = 200 patients). CSF-1 was found at the highest level compared to the other CSF ligands. ( C ) <t>Single-Cell</t> <t>Portal</t> database from Broad Institute was accessed for evaluation of CSF ligand expression. The “Programs, Origins, and Niches of Immunomodulatory Myeloid Cells in Human Gliomas” dataset was used for analysis. Multiple human tumors (85) and cells (515,782) were analyzed. CSF-1 and IL34 are expressed by the malignant cell population. CSF-2 and CSF-3 (GM-CSF and G-CSF) were lowly expressed. Students’ t -test statistical analysis was conducted. Differences are compared to the stimulated control condition. p -values: >0.05 (ns), 0.0332 (*), 0.0002 (***), <0.0001 (****).
    Single Cell Portal Database, supplied by Broad Institute Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/single+cell+portal+database/single+cell+portal+database/pmc11394022-152-0-5
    Average 90 stars, based on 1 article reviews
    single cell portal database - by Bioz Stars, 2026-10
    90/100 stars
      Buy from Supplier

    Image Search Results


    Expression of CSF ligands in murine glioma and human GBM: ( A ) Murine KR158B gliomas express the CSF ligands M-CSF and IL-34 but not GM-CSF. KR158B cells were plated at different numbers (50, 100, 200 thousand) in 24 well plates and the conditioned media were subjected to ELISA after 24 h for cytokine quantification. CSF1R ligands, M-CSF and IL-34, were found at a higher concentration in the media compared to GM-CSF (n = 3 experiments). ( B ) Human GBM expression of CSF ligands was determined from a search of the OncoDB database. TCGA dataset was queried for GBM gene expression. Results were compared to normal brain tissue from GTEx. CSF-1 (M-CSF) was differentially upregulated in the GBM microenvironment (n = 148 patients) compared to normal brain (n = 200 patients). CSF-1 was found at the highest level compared to the other CSF ligands. ( C ) Single-Cell Portal database from Broad Institute was accessed for evaluation of CSF ligand expression. The “Programs, Origins, and Niches of Immunomodulatory Myeloid Cells in Human Gliomas” dataset was used for analysis. Multiple human tumors (85) and cells (515,782) were analyzed. CSF-1 and IL34 are expressed by the malignant cell population. CSF-2 and CSF-3 (GM-CSF and G-CSF) were lowly expressed. Students’ t -test statistical analysis was conducted. Differences are compared to the stimulated control condition. p -values: >0.05 (ns), 0.0332 (*), 0.0002 (***), <0.0001 (****).

    Journal: Cancers

    Article Title: CSF1R Ligands Expressed by Murine Gliomas Promote M-MDSCs to Suppress CD8 + T Cells in a NOS-Dependent Manner

    doi: 10.3390/cancers16173055

    Figure Lengend Snippet: Expression of CSF ligands in murine glioma and human GBM: ( A ) Murine KR158B gliomas express the CSF ligands M-CSF and IL-34 but not GM-CSF. KR158B cells were plated at different numbers (50, 100, 200 thousand) in 24 well plates and the conditioned media were subjected to ELISA after 24 h for cytokine quantification. CSF1R ligands, M-CSF and IL-34, were found at a higher concentration in the media compared to GM-CSF (n = 3 experiments). ( B ) Human GBM expression of CSF ligands was determined from a search of the OncoDB database. TCGA dataset was queried for GBM gene expression. Results were compared to normal brain tissue from GTEx. CSF-1 (M-CSF) was differentially upregulated in the GBM microenvironment (n = 148 patients) compared to normal brain (n = 200 patients). CSF-1 was found at the highest level compared to the other CSF ligands. ( C ) Single-Cell Portal database from Broad Institute was accessed for evaluation of CSF ligand expression. The “Programs, Origins, and Niches of Immunomodulatory Myeloid Cells in Human Gliomas” dataset was used for analysis. Multiple human tumors (85) and cells (515,782) were analyzed. CSF-1 and IL34 are expressed by the malignant cell population. CSF-2 and CSF-3 (GM-CSF and G-CSF) were lowly expressed. Students’ t -test statistical analysis was conducted. Differences are compared to the stimulated control condition. p -values: >0.05 (ns), 0.0332 (*), 0.0002 (***), <0.0001 (****).

    Article Snippet: Single Cell Portal database from Broad Institute was accessed for evaluation of CSF ligand expression.

    Techniques: Expressing, Enzyme-linked Immunosorbent Assay, Concentration Assay, Gene Expression, Control